
Classic Beef Meatloaf with Tangy Glaze
Make Classic Beef Meatloaf with Tangy Glaze, an American dinner recipe with ground beef (80/20 lean), yellow onion, garlic. It has about 1 hr 15 min, about 510 calories per serving. Get ingredients, step-by-step instructions, nutrition estimates, FAQs, and Recipe Genius app tools.
Quick answer
Classic Beef Meatloaf with Tangy Glaze is an American dinner recipe that takes about 1 hr 15 min, makes 6 servings, has about 510 calories per serving. Use the ingredients and steps below, or open it in Recipe Genius for guided Cook Mode, timers, serving changes, and a shopping list.
Recommended gear
As an Amazon Associate, Recipe Genius earns from qualifying purchases.

The easiest way to avoid overcooked chicken, pork, beef, turkey, and fish.
View on Amazon
The one tool that makes chopping vegetables, herbs, meat, and meal prep faster.
View on Amazon
Keeps homemade mixes, dressings, baking, rice, and seasonings consistent.
View on AmazonClassic Beef Meatloaf with Tangy Glaze ingredients
- 2 lbs ground beef (80/20 lean)
- 1 medium yellow onion
- 2 cloves garlic
- 0.75 cup plain breadcrumbs
- 0.5 cup milk
- 1 whole large egg
- 1 tbsp Worcestershire sauce
- 2 tbsp ketchup
- 1.5 tsp kosher salt
- 0.5 tsp black pepper
- 0.5 cup ketchup
- 2 tbsp light brown sugar
- 1 tbsp apple cider vinegar
- 0.5 tsp dry mustard powder
How to make Classic Beef Meatloaf with Tangy Glaze
- Preheat your oven to 375°F (190°C). Lightly grease a rimmed baking sheet or line it with parchment paper for easier cleanup.
- In a small skillet, heat 1 tbsp of olive oil over medium heat. Add the 1 medium finely diced yellow onion and cook for 5-7 minutes until softened and translucent, then add the 2 minced garlic cloves and cook for another minute until fragrant. Remove from heat and let cool slightly.
- In a very large bowl, combine the 2 lbs ground beef, 0.75 cup plain breadcrumbs, 0.5 cup milk, 1 large egg, 1 tbsp Worcestershire sauce, 2 tbsp ketchup, 1.5 tsp kosher salt, and 0.5 tsp black pepper. Add the cooled sautéed onion and garlic.
- Using your hands, gently mix all the meatloaf ingredients until just combined. Be careful not to overmix, as this can make the meatloaf tough. Form the mixture into an even, oblong loaf shape directly on the prepared baking sheet.
- To prepare the tangy glaze, whisk together 0.5 cup ketchup, 2 tbsp light brown sugar, 1 tbsp apple cider vinegar, and 0.5 tsp dry mustard powder in a small bowl until smooth.
- Spread about half of the prepared tangy glaze evenly over the top and sides of the meatloaf.
- Bake the meatloaf in the preheated oven for 45 minutes.
- Remove the meatloaf from the oven. Carefully spread the remaining half of the tangy glaze over the top surface of the meatloaf.
- Return the meatloaf to the oven and continue to bake for another 15-20 minutes, or until the internal temperature reaches 160°F (71°C) when measured with a meat thermometer inserted into the thickest part of the loaf.
- Once baked, remove the meatloaf from the oven and let it rest on the baking sheet for 10-15 minutes. This allows the juices to redistribute, ensuring a moist and flavorful result.
- Slice the meatloaf into thick pieces and serve warm, ideally with mashed potatoes and green beans to complete your classic American dinner.
Classic Beef Meatloaf with Tangy Glaze FAQ
How do I make Classic Beef Meatloaf with Tangy Glaze?
Make Classic Beef Meatloaf with Tangy Glaze by gathering the ingredients below, following the step-by-step instructions, and checking that everything is cooked safely before serving.
What ingredients are in Classic Beef Meatloaf with Tangy Glaze?
The main ingredients include ground beef (80/20 lean), yellow onion, garlic, plain breadcrumbs, milk. The full ingredient list is included on this page.
How long does Classic Beef Meatloaf with Tangy Glaze take?
This recipe takes about 1 hr 15 min, depending on prep speed and kitchen equipment.
How many calories are in Classic Beef Meatloaf with Tangy Glaze?
Recipe Genius estimates about 510 calories per serving. Nutrition is estimated, so use your own labels when precision matters.
More recipes you might like
Browse related collections
Cook smarter with Recipe Genius
Generate recipes, build meal plans, and create shopping lists with Recipe Genius.